Tyldesley is a town in the Metropolitan Borough of Wigan in Greater Manchester, England.

Within the boundaries of the historic county of Lancashire, it is north of Chat Moss near the foothills of the West Pennine Moors, 7.7 miles (12.4 km) southeast of Wigan and 8.9 miles (14.3 km) northwest of Manchester.

Tyldesley has a resident population of 14,920 which represents 4.5% of the total Wigan resident population of 330,712. 16% of the residents in Tyldesley, Astley and Mosley Common are made up of people aged 65+, lower than the borough average of 17.6%. 10.1% of households are aged 65+ and live alone compared with 11.7% of the borough households.

Tyldesley is made up of 16 smaller areas one of which (Shakerley) is ranked within the top 10% most deprived in England according to the Indices of Multiple Deprivation. 4 areas are ranked within the top 20% most affluent in England these include Chaddock Lane, New Hall, Tyldesley South and Bodmin Road. 12.8% of residents claim out of work benefits, below the borough average of 15.9%.

73% of residents either own their homes outright or have a mortgage, 15% of households live in social rented accommodation.